Contemporary Approaches to Inflammatory Arthritis Peer-to-Peer
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Predicting Juvenile Idiopathic Arthritis Activity
In a study that included more than 1100 participants with juvenile idiopathic arthritis, researchers in Seattle pinpointed a number of factors that may indicate an increased likelihood of active disease at 12- and 24-months post diagnosis.
Personalized Exercise for Patients with Axial Spondyloarthritis and Severe Functional Limitations
Exercise therapy is recommended for patients with axial spondyloarthritis, but there is limited research in the sub-set of patients with axSpA and severe functional limitations. These investigators assessed the efficacy of a 52-week personalized exercise therapy regimen, and the findings are promising.
Is Pediatric Acute-Onset Neuropsychiatric Syndrome a Systemic Inflammatory Condition?
In a large retrospective study of children with PANS, researchers found a high rate of immune activation signs, vasculopathy signs, and a high prevalence of arthritis and other autoimmune diseases developing later in childhood.
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Vaccinating Inflammatory Arthritis Patients: What Are The Current Recommendations?
Anand Kumthekar, MD, of Albert Einstein College of Medicine, discusses the American College of Rheumatology's latest vaccination guidelines for inflammatory arthritis. (2:15)
Psoriatic Disease: Understanding The New Vaccination Guidelines
Clinicians have received updated guidance on which vaccines are necessary and safe for their patients with psoriatic disease for the first time in a decade.
Are Veterans Getting Timely Arthritis Treatment?
An observational cohort study of U.S. military veterans with rheumatoid arthritis, psoriatic arthritis, or ankylosing spondylitis examined missed opportunities for treatment of inflammatory arthritis and why they’re happening.
Inflammatory Rheumatic Disease: How Anxiety and Depression Impact Self-Care
Screening for mental health issues might be appropriate in routine care as a first step in addressing obstacles to poor self-management and adverse outcomes, according to this study.
Confirming a Psoriatic Arthritis Diagnosis: How Long is Too Long?
Do you suspect that a patient may have psoriatic arthritis? If so, sort out the diagnosis promptly.
Aortic Vascular Inflammation Increased in Psoriatic Arthritis Patients
Researchers comparing measures of vascular inflammation in patients with PsA and healthy controls using FDG PET/CT scans found significant increases in inflammation in patients compared with healthy controls. Is this an underlying factor for the increased risk of CVD in PsA?
Psoriatic Arthritis Phenotypes and Disease Activity: Ethnic and Racial Components
A team of researchers based in New York City assessed whether presentation of psoriatic arthritis and its disease course differ in White and non-White populations. Here’s what they found.
PsA and Racial Differences: Comorbidities Not Driven Only by Disease Activity
A recent study of patients with PsA in the US showed increased comorbidities in African American patients compared with Caucasians.
Assessing Disease Activity in Axial Spondyloarthritis
Anand Kumthekar, MD, of the Albert Einstein College of Medicine, discusses the two main disease activity measures he uses in his spondyloarthritis patients. (2:16)
Rheumatoid Arthritis and Axial Spondyloarthritis: What are the Biggest Challenges for Patients?
Patients with either of these conditions have to endure reduced mobility. But which activities of daily living are the most difficult to perform? A study based on patient feedback provides some fresh insight.
Immune-Mediated Inflammatory Disease: Assessing Prevalence Across Different Patient Groups
These authors used EHR data to determine which IMIDs are most prevalent overall, as well as within specific racial and ethnic groups. They also assessed whether the racial and ethnic associations are modified by other factors, such as age and sex.
For Axial Spondyloarthritis Patients, More Exercise May Mean Better Sleep
This cross-sectional study showed that reduced sleep quality, though common in axSpA patients, was improved with better physical function and higher cardiorespiratory fitness.
Axial Spondyloarthritis Diagnosis Hampered by Socioeconomic Vulnerability, Clinical Issues
Harvard investigators found that patients with axSpA often experience a significant delay between symptom onset and diagnosis. This study highlights some of the reasons.
Psoriasis is Frequently Underdiagnosed in Patients with Axial Spondyloarthritis
Patient-reported psoriasis symptoms are common in axSpA cohorts, but many patients lack formal diagnosis likely due to subtle or atypical manifestations. Proactive screening is essential for detection and integrated treatment of both joint and skin disease.
Early Onset of Spondyloarthritis Symptoms Challenges Diagnostic Delay
Patients with early onset of extra-musculoskeletal manifestations, such as psoriasis, may face shorter diagnostic delays compared to those who have more common musculoskeletal symptoms, which could enable quicker spondyloarthritis diagnosis and treatment.
Axial Spondyloarthritis With Psoriasis and Axial Psoriatic Arthritis: How Different is Different?
These conditions have overlapping features, which has raised the possibility that they are on the same disease spectrum. A new study, however, shows distinct demographic, clinical, and genetic aspects suggesting they are discrete disease entities.
Tackling Treatment Resistance in Axial Spondyloarthritis
Abhijeet Danve, MD, MHS, of Yale School of Medicine, discusses the steps clinicians should take when axSpA patients don't respond well to treatment. (1:49)
Axial Spondyloarthritis Treatment May Not Always Reflect Guidelines in Daily Practice
A study in the Netherlands found the guideline-recommended strategy of treat-to-target in patients with axial spondyloarthritis is not widely implemented by clinicians.
What Happens When Patients with Juvenile Idiopathic Arthritis Become Adults?
Reclassifying adults with juvenile idiopathic arthritis may have the advantage of exposing them sooner to a wider spectrum of disease-modifying drugs, possibly improving long-term outcomes.
Q&A: Marina Magrey, MD, on Surveying Patients with axSpA About Their Real-life Experiences
Dr. Magrey, of Case Western Reserve University, discusses her latest research on patients’ experiences of axial spondyloarthritis.
In Axial Spondyloarthritis, Clinical and Imaging Features Differ by Gender
This study reported clinical and radiographic findings in 91 patients from the SPACE cohort study followed over a 4-year period. Men were more likely to demonstrate radiographic progression of sacroiliitis and spinal disease on X-ray and MRI, while women were more likely demonstrate cervical and thoracic disease on MRI.
Self-Reported vs Performance-Based Assessments for Axial Spondyloarthritis
Scientists compared self-reported and performance-based physical function assessment and investigated the most common impairments among those with axial spondyloarthritis.
Q&A—Marina N. Magrey, MD on Diagnostic Missteps in Axial Spondyloarthritis
Marina N. Magrey, MD, Professor of Medicine at Case Western Reserve University and Division Chief of Rheumatology at University Hospitals in Cleveland, discusses the many speed bumps on the road to a diagnosis of axSpA and how close we may be to resolving some of them.
Syndesmophytes Less Likely in Women and Those with Early Onset Ankylosing Spondylitis
Women, patients who have symptom onset before the age of 16 years, and those without HLA-B27 positivity are less likely to develop syndesmophytes in association with AS, despite the presence of joint fusion.
Axial Spondyloarthritis Leads to Work-related Physical and Psychological Burdens
Work-related issues for patients with axSpA are associated with worse patient-reported outcomes, both physical and psychological. Disability benefits may improve many of these situations.
Do Extra-articular Manifestations Increase Cardiovascular Risk in Axial Spondyloarthritis?
Patients with axial spondyloarthritis and coexisting extraarticular manifestations have an increased CV risk. Inflammation level and glucocorticoid use contribute to this higher risk.