Peer to Peer: Spotlight on AMD
Age-Related Macular Degeneration and Dementia Medications: Are They Linked?
Investigators assembled multiple UK cohorts to analyze a possible protective effect of dementia medications on age-related macular degeneration.
Are Age-Related Eye Diseases Triggered by Ultra-processed Foods?
A new study from China concluded that higher consumption of ultra-processed foods is associated with an increased risk of age-related macular degeneration, cataracts, and glaucoma.
Geographic Atrophy: The Effects of Lesion Location and Functional Deficits
The location of vision loss within the central retina has a significant impact on daily life in patients with geographic atrophy. With this in mind, a new study examined structural and functional parameters to gain valuable insights into the challenges faced by those with this condition.
An Updated Polygenic Risk Score for AMD: How Well Does It Work?
That was the question pondered by a team of researchers in Australia, who set out to determine whether the newly revised polygenic risk score for age-related macular degeneration is an improvement over its predecessor.
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Which AMD Patients Progress to Geographic Atrophy?
Sarju Patel, MD, discusses late-stage dry macular degeneration and potential risk factors for geographic atrophy. (3:10)
Pachydrusen in Age-Related Macular Degeneration: Understanding a Distinct Risk Profile
Eyes with pachydrusen, a specific type of drusen deposit, may develop a less aggressive form of age-related macular degeneration.
nAMD: Do Home-Monitoring Tests Effectively Detect Reactivations?
The three home-monitoring visual function tests evaluated were not accurate enough to be used for detecting reactivation of neovascular age-related macular degeneration.
In AMD, Patient-Perceived Communication Gaps May Lower Quality of Care
A study from the Netherlands concluded that patients with age-related macular degeneration often fail to understand their chronic condition and need clearer, more-tailored information from their healthcare team.
Patients with Cataract, AMD, and Glaucoma are Falling Down—A Lot
Patients with cataract, AMD, or glaucoma are at greatly increased risk for falls. In this large multicohort, population-based study, no body site was spared, with fractures noted at the hip, spine, forearm, skull, facial bones, pelvis, ribs, sternum, and lower leg.
The Impact of Delayed Neovascular AMD Treatment During COVID
Investigators retrospectively examined AMD patients whose treatment was delayed during the COVID-19 pandemic to assess the impact of delayed injections.
UV Radiation and Age-Related Macular Degeneration Risk
These investigators found that cumulative lifetime exposure to intermediate levels of ultraviolet radiation was associated with an increased risk of early age-related macular degeneration.
The Double Layer Sign: Can It Predict Conversion to Wet Age-Related Macular Degeneration?
Spectral domain-optical coherence tomography (OCT) images from the Early Detection of Neovascular AMD study were recently reanalyzed for the double-layer sign and 2 other OCT biomarkers, assessing their ability to predict progression to exudative macular neovascularization. Here’s what was learned.
Age-Related Macular Degeneration: Do Americans “Get” It?
Apparently not, according to the results of a new study, which found that fewer than 1 in 5 patients knew that they had a diagnosis of AMD, with younger patients being unaware at much higher rates than older patients.
Shining Light On AMD Risk Factors
Residential nighttime outdoor artificial light can have a significant impact on the risk of exudative AMD.
AMD and Brain Atrophy: Q&A with Drs. Stout, Whitson, and Badea of Duke University
People with late-life vision impairment, specifically from AMD, are at higher risk of subsequent cognitive decline. These investigators from Duke University explain what they’re learning about this phenomenon.
Patients With Cataract, AMD, and Glaucoma Suffer Greater Risk of Falls and Fractures
A study from the UK showed patients with cataract, AMD, or glaucoma have up to a 100% increased risk for falls and fractures compared with patients without these eye diseases.
In Age-Related Macular Degeneration, Can This Common Alzheimer’s Drug Reduce the Risk?
Military veterans receiving acetylcholinesterase inhibitor treatment for Alzheimer’s disease exhibited reduced risk of age-related macular degeneration, according to this study.
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Age-Related Macular Degeneration and Alzheimer’s Disease: Is There a Connection?
Sarju Patel, MD, MPH, MSc, discusses the biologic overlap between Alzheimer's Disease and macular degeneration. "There's still much to be worked out," he tell us. (2:12)
Road Blocks to Sight-Saving Injections: What’s Getting in the Way of AMD Treatment?
Inadequate adherence to AMD treatment can have devastating consequences, and one of the main obstacles is proximity to treatment centers. By understanding the challenges faced by patients living far from treatment centers, targeted interventions to improve adherence can be developed to preserve vision.
AMD Development in Patients with AIDS: NLRP3 Inflammasome Activation May Play a Role
Elevated systemic biomarkers linked to the innate immune system were associated with development of intermediate AMD onset but not age-related cataracts in people with AIDS, suggesting chronic inflammation may accelerate retinal aging more than normal aging alone.
Improving the Odds of Predicting AMD Risk
A team of researchers in Australia was able to pinpoint novel loci for age-related macular degeneration (AMD) and develop a new polygenic risk score that was shown to improve AMD risk prediction.
In Age-Related Macular Degeneration, Can Metformin Help Treat Patients Without Diabetes?
Metformin decreases the odds of age-related macular degeneration development in patients without diabetes, according to this analysis.