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Sepsis

News, opinions and meeting coverage in critical care.

SCCM over a photo of Phoenix Convention Center

Newly Unveiled Criteria for Pediatric Sepsis Can Improve Diagnoses

The Phoenix Sepsis Score was validated using encounters in higher- and lower-resource settings

A photo of a petri dish containing Burkholderia pseudomallei

CDC Tracks Down Rare, Deadly Bacteria in Mississippi Gulf Region

Locating the bacteria that causes melioidosis akin to "finding a needle in a haystack"

A computer rendering of bacterial transduction.

To Get More New Antimicrobial Drugs, Fix the Broken Market, Experts Say

Hospitals see a new antibiotic as something to raise their costs, one expert noted

A photo of a female nurse adjusting the medication of an ICU patient.

Infectious Disease Groups Urge CMS to Retire Sepsis Treatment Guidelines

Use of the measure hasn't lowered mortality rates, they say

AAP over a photo of Walter E. Washington Convention Center in Washington, DC.

Black Kids Twice as Likely to Die of Sepsis, Single-Center Study Finds

"Outcomes were different" even with similar care, says researcher

IDWeek over a photo of Boston Convention & Exhibition Center - Boston, MA.

Antibiotic Combo for Acute Infection Cleared of Kidney Risk

Use of cefepime meanwhile resulted in more neurological dysfunction

A computer rendering of bacteria in the bloodstream.

Feds Hope to Cut Sepsis Deaths by Hitching Medicare Payments to Treatment Stats

Treatment delays can undermine a patient's chance of survival

CHEST over a photo of the Hilton Hawaiian Village Waikiki Beach Resort in Honolulu, HI.

'Surprising' Contribution of Pulmonary Hypertension to ARDS Outcomes

Coexisting conditions spell markedly poor clinical course

A computer rendering of bacteria in the bloodstream.

CDC Issues Sepsis Care Guidance for Hospitals

Every hospital can strengthen the quality of care delivered to these patients, says CDC director

A photo of Madonna in the press room at the 2018 MTV Video Music Awards

Madonna's ICU Stay May Have Been Due to Sepsis

Despite being life-threatening, sepsis can be easy to miss

A photo of an intubated male patient in the intensive care unit.

Sepsis Outcomes No Different With Prolonged Beta-Lactam Antibiotic

Death and drug resistance unchanged no matter the duration of treatment

A photo of a nurse tending to a patient in the ICU.

More RN Hours Linked With Better Sepsis Outcomes

Facility needs to have enough nurses on staff for such "complex care," researcher warns

A photo of a blue rubber gloved hand holding a vial of blood labeled: PRESEPSIN TEST

Presepsin a 'Robust' Biomarker of Early-Onset Sepsis

Researchers call for trials testing its use in guiding early empirical antibiotic treatment

INVESTIGATIVE ROUNDUP over an image of two people looking at computer screens.

Epic's AI Fail; Controversial Alzheimer's Marketing; No Good COVID Drugs

This past week in healthcare investigations

SCCM over a photo of doctors rushing a patient on a gurney into the ER

Sepsis in Children Better Controlled with Care Bundles

Also: living in low-income neighborhoods linked to longer hospital stays

The Bradykinin molecular structure over a computer rendering of the coronavirus

COVID-19 Storms: Bradykinin In, Cytokine Out?

Papers poke holes in cytokine storm as gene expression study offers a new theory

A box and blister pack of oral corticosteroids

Sobering Data on Risks of Short-Term Oral Corticosteroids

Short steroid bursts linked to serious adverse events within a month

A computer rendering of a cell releasing exosomes

Serious Illnesses in Nebraska Tied to Exosome Therapy

New trend in unapproved stem cell therapy led to sepsis in some patients

A computer rendering of Clostridium difficile

Study: Fecal Transplants Cut Sepsis Risk in Patients With C. Diff

FMT also tied to shorter length of hospital stay, better overall survival vs antibiotics

Gram negative bacterial bloodstream infection seen through a microscope

Antibiotics vs Blood Cultures in Sepsis: Which Should Come First?

Study addresses whether immediate treatment plays a role in diagnostic sensitivity

3D illustration showing sepsis in blood with rod-shaped bacteria with red blood cells and leukocytes.

Sepsis Survivors Not Out of the Woods

Patient age, sex, and higher APACHE II scores tied to intermediate-term mortality

A photo composition of Carmen Puliafito, MD and some college girls at a pool party.

USC Party Dean Gets $1.8M; TV Doc Disciplined; Fla. 3-Strike Law Fails

Bad Practice: a weekly roundup of clinicians accused, convicted, or under investigation

How Best to Monitor Critically Ill Patients?

Continuous surveillance achieved through EHR data could provide key insights

Similar Endotypes Identified for Pediatric ARDS and Sepsis

Shared biology between children with sepsis, respiratory failure could predict mortality risk, study shows

Antibiotics Rx Common, but Variable, in Pediatric ICU

Children given antibiotics were on mechanical ventilation for fewer days

Peripheral Perfusion Fails to Cut Septic Shock Mortality

But showed improvements over lactate-guided resuscitation for some outcomes

CDC May Have a Better Mousetrap for Sepsis Surveillance

Researchers compare the CDC's simplified criteria against SOFA criteria

Rapid Genetic Test May Prevent Abx-Linked Hearing Loss in Babies

For newborns with sepsis,identifies those at risk from aminoglycosides

Vasopressin Lowers Sepsis Afib Risk

Addition to shock treatment may offer clinical advantage

Seizure Risk After Sepsis Lasts for Years

Far above rates seen in non-sepsis patients, especially at younger ages

Mortality High in Post-Arthroplasty Sepsis

Sources of sepsis included pneumonia and urinary tract or surgical site infections

New Sepsis Definition a Work in Progress

Monday's document not the last word on subject

10 Things ICUs Must Do Better

Compassion tops the list by former Society of Critical Care Medicine president.

Does Tylenol Protect Kidneys in Sepsis?

SAN DIEGO -- Acetaminophen (Tylenol) for severe sepsis patients improved renal function but gave mixed signals in terms of changes in the expected oxidative injury mechanism, researchers found in a pilot trial.